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A protein synthesis and nitric oxide-dependent presynaptic enhancement in persistent forms of long-term potentiation

Johnstone, Victoria; Raymond, Clarke


Long-term potentiation (LTP) is an important process underlying learning and memory in the brain. At CA3-CA1 synapses in the hippocampus, three discrete forms of LTP (LTP1, 2, and 3) can be differentiated on the basis of maintenance and induction mechanisms. However, the relative roles of pre- and post-synaptic expression mechanisms in LTP1, 2, and 3 are unknown. Neurotransmitter release in the expression of LTP1, 2, and 3 was measured via FM 1-43 destaining from CA3 terminals in hippocampal...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Learning and Memory
DOI: 10.1101/lm.2245911


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