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Novel folding and stability defects cause a deficiency of human glutathione transferase omega 1

Zhou, Huina; Brock, Joseph; Casarotto, Marco; Oakley, Aaron; Board, Philip

Description

The polymorphic deletion of Glu-155 from human glutathione transferase omega1 (GSTO1-1) occurs in most populations. Although the recombinant ΔGlu-155 enzyme expressed in Escherichia coli is active, the deletion causes a deficiency of the active enzyme in

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/58587
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M110.197822

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