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Modulation of excitability by α-dendrotoxin-sensitive potassium channels in neocortical pyramidal neurons

Bekkers, John; Delaney, Andrew James


Many neurons transduce synaptic inputs into action potentials (APs) according to rules that reflect their intrinsic membrane properties. Voltage-gated potassium channels, being numerous and diverse constituents of neuronal membrane, are important participants in neuronal excitability and thus in synaptic integration. Here we address the role of dendrotoxin-sensitive "D-type" potassium channels in the excitability of large pyramidal neurons in layer 5 of the rat neocortex. Low concentrations of...[Show more]

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
Source: Journal of Neuroscience


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