Estimating the dielectric constant of the channel protein and pore
When modelling biological ion channels using Brownian dynamics (BD) or Poisson-Nernst-Planck theory, the force encountered by permeant ions is calculated by solving Poisson's equation. Two free parameters needed to solve this equation are the dielectric constant of water in the pore and the dielectric constant of the protein forming the channel. Although these values can in theory be deduced by various methods, they do not give a reliable answer when applied to channel-like geometries that...[Show more]
|Collections||ANU Research Publications|
|Source:||European Biophysics Journal|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.