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Large-scale Dynamical Models and Estimation for Permeation in Biological Membrane Ion Channels

Krishnamurthy, Vikram; Chung, Shin-Ho


Biological ion channels are water-filled angstrom-unit (1 angstrom unit=10-10 m)sized pores formed by proteins in the cell membrane. They are responsible for regulating the flow of ions into and out of a cell and hence they control all electrical activities in a cell. This paper deals with constructing large scale stochastic dynamical models for explaining ion permeation; that is, how individual ions interact with the protein atoms in an ion channel and travel through the channel. These...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Proceedings of the IEEE
DOI: 10.1109/JPROC.2007.893246


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