Skip navigation
Skip navigation

Dendritic coincidence detection of EPSPs and action potentials

Stuart, Gregory J; Hausser, Michael


We describe a mechanism for coincidence detection mediated by the interaction between backpropagating action potentials and EPSPs in neocortical pyramidal neurons. At distal dendritic locations, appropriately timed EPSPs or oscillations could increase the amplitude of backpropagating action potentials by three- to fourfold. This amplification was greatest when action potentials occurred at the peak of EPSPs or dendritic oscillations and could lead to somatic burst firing. The increase in...[Show more]

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
Source: Nature Neuroscience
DOI: 10.1038/82910


There are no files associated with this item.

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator