A First Generation Chemoenzymatic Synthesis of (+)-Galanthamine
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Banwell, Martin; Ma, Xinghua; Karunaratne, Ochitha; Willis, Anthony
Description
A total synthesis of (+)-galanthamine [(+)-1] has been achieved using the readily available and enantiomerically pure metabolite 2 as starting material. The quaternary carbon centre (C8a) associated with target 1 was constructed using the EschenmoserClaisen rearrangement reaction.
Collections | ANU Research Publications |
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Date published: | 2010 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/57635 |
Source: | Australian Journal of Chemistry |
DOI: | 10.1071/CH10201 |
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01_Banwell_A_First_Generation_2010.pdf | 394.21 kB | Adobe PDF | Request a copy |
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