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Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

Mikkelsen, Tarjei S; Wakefield, Matthew; Aken, Bronwen; Amemiya, Chris T; Chang, Jean L; Duke, Shannon; Garber, Manuel; Gentles, Andrew J; Goodstadt, Leo; Heger, Andreas; Jurka, Jerzy; Kamal, Michael; Mauceli, Evan; Searle, Stephen M J; Sharpe, Ted; Baker, Michelle L; Batzer, Mark A; Benos, Panayiotis; Belov, Katherine; Clamp, Michele; Cook, April; Cuff, James; Das, Radhika; Davidow, Lance; Deakin, Janine; Fazzari, Melissa J; Glass, Jacob L; Grabherr, Manfred; Greally, John M; Gu, Wanjun; Hore, Tim; Huttley, Gavin Austin; Kleber, Michael; Jirtle, Randy L; Koina, Edda; Lee, Jeannie T; Mahoney, Shaun; Marra, Marco A; Miller, Robert D; Nicholls, Robert D; Oda, Mayumi; Papenfuss, Anthony T; Parra, Zuly E; Pollock, David D; Ray, David A; Schein, Jacqueline E; Speed, Terence P; Thompson, Katherine; VandeBerg, John L; Wade, Claire M; Walker, Jerilyn A; Waters, Paul; Webber, Caleb; Weidman, Jennifer R; Xie, Xiaohui; Zody, Michael C; Graves, Jennifer; Ponting, Chris P; Breen, Matthew; Samollow, Paul; Lander, Eric S; Lindblad-Toh, Kerstin


We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis domestica). As the first metatherian ('marsupial') species to be sequenced, the opossum provides a unique perspective on the organization and evolution of mammalian genomes. Distinctive features of the opossum chromosomes provide support for recent theories about genome evolution and function, including a strong influence of biased gene conversion on nucleotide sequence composition, and a...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Nature
DOI: 10.1038/nature05805


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