Recruitment of old genes to new functions: evidences obtained by comparing the orthologues of human XLMR genes in mouse and chicken
Gene mapping data indicate that the human X chromosome is enriched in genes that affect both, higher cognitive efficiency and reproductive success. This raises the question whether these functions are ancient, or whether conserved X-linked genes were recruited to new functions. We have studied three X-linked mental retardation (XLMR) genes by RNA in situ hybridization in mouse and in chicken, in which these genes are autosomal: Rho guanine nucleotide exchange factor 6 (ARHGEF6), oligophrenin...[Show more]
|Collections||ANU Research Publications|
|Source:||Cytogenetic and Genome Research|
|01_Kohn_Recruitment_of_old_genes_to_2007.pdf||3.08 MB||Adobe PDF||Request a copy|
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