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Association of hypotension with positive and negative effect and depressive symptoms in the elderly

Jorm, Anthony F

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Background: Previous research associating hypotension with depression has produced inconsistent results. A possible reasons is that depressive symptom scales reflect both high negative affect and low positive affect. Aims: To examine the association of hypotension with depressive symptoms, negative affect and positive affect. Method: Community survey of 340 elderly persons aged 77-99 years. Results: Diastolic hypotension had a weak association with depression, no association with negative...[Show more]

dc.contributor.authorJorm, Anthony F
dc.date.accessioned2015-12-10T22:38:25Z
dc.identifier.issn0007-1250
dc.identifier.urihttp://hdl.handle.net/1885/56751
dc.description.abstractBackground: Previous research associating hypotension with depression has produced inconsistent results. A possible reasons is that depressive symptom scales reflect both high negative affect and low positive affect. Aims: To examine the association of hypotension with depressive symptoms, negative affect and positive affect. Method: Community survey of 340 elderly persons aged 77-99 years. Results: Diastolic hypotension had a weak association with depression, no association with negative affect and a strong inverse association with positive affect. Systolic hypertension was associated with positive affect. Use of antihypertensive medication was independently associated with lower positive affect, Conclusions: Diastolic hypotension shows a specific association with low positive affect. This association may explain the weak and inconsistent results of earlier studies relating hypotension to depression. Declaration of interest: Funding was provided by the National Health and Medical Research Council and the Australian Rotary Health Research Fund.
dc.publisherRoyal College of Psychiatrists
dc.sourceBritish Journal of Psychiatry
dc.subjectKeywords: antihypertensive agent; affect; aged; aging; article; correlation function; depression; diastole; disease association; female; human; hypotension; major clinical study; male; rating scale; systolic hypertension; Affect; Aged; Aged, 80 and over; Antihypert
dc.titleAssociation of hypotension with positive and negative effect and depressive symptoms in the elderly
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume178
dc.date.issued2001
local.identifier.absfor111714 - Mental Health
local.identifier.ariespublicationMigratedxPub374
local.type.statusPublished Version
local.contributor.affiliationJorm, Anthony F, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpage553
local.bibliographicCitation.lastpage555
local.identifier.doi10.1192/bjp.178.6.553
dc.date.updated2015-12-09T10:39:52Z
local.identifier.scopusID2-s2.0-0034994999
CollectionsANU Research Publications

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