Bose, Bhadran; Badve, Sunil V.; Hiremath, Swapnil S.; Boudville, Neil; Brown, Fiona G.; Cass, Alan; de Zoysa, Janak R.; Fassett, Robert G.; Faull, Randall; Harris, David C.; Walters, Giles
Background. Non-randomized studies suggest an association between serum uric acid levels and progression of chronic kidney disease (CKD). The aim of this systematic review is to summarize evidence from randomized controlled trials (RCTs) concerning the benefits and risks of uric acid-lowering therapy on renal outcomes. Methods. Medline, Excerpta Medical Database and Cochrane Central Register of Controlled Trials were searched with English language restriction for RCTs comparing the effect of...[Show more]
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