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Effects of uric acid-lowering therapy on renal outcomes: a systematic review and meta-analysis

Bose, Bhadran; Badve, Sunil V.; Hiremath, Swapnil S.; Boudville, Neil; Brown, Fiona G.; Cass, Alan; de Zoysa, Janak R.; Fassett, Robert G.; Faull, Randall; Harris, David C.; Walters, Giles


Background. Non-randomized studies suggest an association between serum uric acid levels and progression of chronic kidney disease (CKD). The aim of this systematic review is to summarize evidence from randomized controlled trials (RCTs) concerning the benefits and risks of uric acid-lowering therapy on renal outcomes. Methods. Medline, Excerpta Medical Database and Cochrane Central Register of Controlled Trials were searched with English language restriction for RCTs comparing the effect of...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Nephrology Dialysis Transplantation
DOI: 10.1093/ndt/gft378


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