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The total synthesis of (−)-tetrahydrolipstatin (Short Communication)

Bodkin, Jennifer A; Humphries, Edward; McLeod, Malcolm

Description

Careful control during the bromolactonisation of β,γ-unsaturated acid 3 was required to afford regioselectively the trans-β-lactone 4 as the major diastereomer. Radical debromination of 4 followed by a three-step sequence of reactions afforded the lipa

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/56725
Source: Tetrahedron Letters
DOI: 10.1016/S0040-4039(03)00443-X

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