Larsen, M.B.; Stephens, Ross; Brunner, N; Nielsen, H.J.; Engelholm, L.H.; Christensen, I.J.; Stetler-Stevenson, W.G.; Høyer-Hansen, G
Tissue inhibitor of metalloproteinases (TIMP)-2 is a highly conserved molecule, which binds both active and latent matrix metalloproteinase (MMP)-2. TIMP-2 is also involved in the activation of MMP-2 on the cell surface. A quantitative enzyme-linked immunosorbent assay (ELISA) was established and optimized for measurement of TIMP-2 in plasma. The capturing antibody in the ELISA was a monoclonal, while the detecting antibody was a chicken polyclonal antibody recognizing the native form of human...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.