Skip navigation
Skip navigation

Structure of the adenylylation domain of E. coli glutamine synthetase adenylyl transferase: evidence for gene duplication and evolution of a new active site

Xu, Yibin; Carr, Paul D; Vasudevan, Subhash; Ollis, David


The X-ray structure of the C-terminal fragment, containing residues 449-946, of Escherichia coli glutamine synthetase adenylyl transferase (ATase) has been determined. ATase is part of the cascade that regulates the enzymatic activity of E. coli glutamine synthetase, a key component of the cell's machinery for the uptake of ammonia. It has two enzymatic activities, adenylyl removase (AR) and adenylyl transferase (AT), which are located in distinct catalytic domains that are separated by a...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Journal of Molecular Biology
DOI: 10.1016/j.jmb.2009.12.011


File Description SizeFormat Image
01_Xu_Structure_of_the_adenylylation_2010.pdf2.23 MBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator