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Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice

Huynh, Tony; Uaesoontrachoon, Kitipong; Quinn, James; Tatem, Kathleen S; Heier, Christopher; Van Der Meulen, Jack H; Yu, Qing; Harris, Mark; Nolan, Christopher; Haegeman, Guy; Grounds, Miranda D; Nagaraju, Kanneboyina


The over-expression of NF-κB signalling in both muscle and immune cells contribute to the pathology in dystrophic muscle. The anti-inflammatory properties of glucocorticoids, mediated predominantly through monomeric glucocorticoid receptor inhibition of

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Journal of Pathology
DOI: 10.1002/path.4231


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