Integrated research into the nanoparticle-protein corona: a new focus for safe, sustainable and equitable development of nanomedicines
White, John; Matthaei, Klaus; Faunce, Thomas
Much contemporary nanotoxicology, nanotherapeutic and nanoregulatory research has been characterized by a focus on investigating how delivery of engineered nanoparticles (ENPs) to cells is dictated primarily by components of the ENP surface. An alternative model, some implications of which are discussed here, begins with fundamental physicochemical research into the interaction of a dynamic nanoparticle-protein corona (NPC) with biological systems. The proposed new model also requires, however,...[Show more]
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