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Randomized trial of guiding hypertension management using central aortic blood pressure compared with best-practice care: principal findings of the BP GUIDE study

Sharman, James E.; Marwick, Thomas H.; Gilroy, Deborah; Otahal, Petr; Abhayaratna, Walter; Stowasser, Michael


Arm cuff blood pressure (BP) may overestimate cardiovascular risk. Central aortic BP predicts mortality and could be a better method for patient management. We sought to determine the usefulness of central BP to guide hypertension management. This was a prospective, open-label, blinded-end point study in 286 patients with hypertension randomized to treatment decisions guided by best-practice usual care (n=142; using office, home, and 24-hour ambulatory BP) or, in addition, by central BP...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Hypertension
DOI: 10.1161/HYPERTENSIONAHA.113.02001


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