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Strain dependence of diet-induced NASH and liver fibrosis in obese mice is linked to diabetes and inflammatory phenotype

Farrell, Geoffrey; Mridha, Auvro; Yeh, Matthew; Arsov, Todor; Van Rooyen, Derrick; Brooling, John; Nguyen, Tori; Heydet, Deborah; Delghingaro-Augusto, Viviane; Nolan, Christopher; Shackel, Nicholas; McLennan, Susan V; Teoh, Narcissus; Larter, Claire


Background & Aims: Obese Alms1 mutant (foz/foz) NOD.B10 mice develop diabetes and fibrotic NASH when fed high-fat(HF) diet. To establish whether diabetes or obesity is more closely associated with NASH fibrosis, we compared diabetic foz/foz C57BL6/J with

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Liver International
DOI: 10.1111/liv.12335


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