The impact of glutathione transferase kappa deficiency on adiponectin multimerisation in vivo
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Theodoratos, Angelo; Blackburn, Anneke; Coggan, Marjorie; Cappello, Jean; Larter, Claire; Matthaei, Klaus; Board, Philip
Description
Glutathione transferase Kappa (GSTK1-1) also termed disulfide bond-forming oxidoreductase A-like protein (DsbA-L) has been implicated in the post-translational multimerization of adiponectin and has been negatively correlated with obesity in mice and humans. We investigated adiponectin in Gstk1-/- mice and surprisingly found no difference in the levels of total serum adiponectin or the level of high molecular weight (HMW) multimers when compared with normal controls. Non-reducing...[Show more]
Collections | ANU Research Publications |
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Date published: | 2012 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/54237 |
Source: | International Journal of Obesity |
DOI: | 10.1038/ijo.2011.267 |
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01_Theodoratos_The_impact_of_glutathione_2012.pdf | 217.74 kB | Adobe PDF | Request a copy |
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