The impact of glutathione transferase kappa deficiency on adiponectin multimerisation in vivo
Glutathione transferase Kappa (GSTK1-1) also termed disulfide bond-forming oxidoreductase A-like protein (DsbA-L) has been implicated in the post-translational multimerization of adiponectin and has been negatively correlated with obesity in mice and humans. We investigated adiponectin in Gstk1-/- mice and surprisingly found no difference in the levels of total serum adiponectin or the level of high molecular weight (HMW) multimers when compared with normal controls. Non-reducing...[Show more]
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|Source:||International Journal of Obesity|
|01_Theodoratos_The_impact_of_glutathione_2012.pdf||217.74 kB||Adobe PDF||Request a copy|
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