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Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells

Sun, Ramon; Board, Philip; Blackburn, Anneke

Description

Background: Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of cancer and

dc.contributor.authorSun, Ramon
dc.contributor.authorBoard, Philip
dc.contributor.authorBlackburn, Anneke
dc.date.accessioned2015-12-10T22:27:26Z
dc.identifier.issn1535-7163
dc.identifier.urihttp://hdl.handle.net/1885/54201
dc.description.abstractBackground: Cancer cells have a different metabolic profile compared to normal cells. The Warburg effect (increased aerobic glycolysis) and glutaminolysis (increased mitochondrial activity from glutamine catabolism) are well known hallmarks of cancer and
dc.publisherAmerican Association for Cancer Research
dc.sourceMolecular Cancer Therapeutics
dc.subjectKeywords: adenosine triphosphate; arsenic trioxide; cytochrome c oxidase; dichloroacetic acid; hypoxia inducible factor 1alpha; Myc protein; proton transporting adenosine triphosphatase; reactive oxygen metabolite; adenosine triphosphate; antineoplastic agent; arse Arsenic trioxide; Breast cancer; Dichloroacetate; Electron transport chain; Mitochondria
dc.titleTargeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume10
dc.date.issued2011
local.identifier.absfor111207 - Molecular Targets
local.identifier.ariespublicationu4020362xPUB294
local.type.statusPublished Version
local.contributor.affiliationSun, Ramon, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationBoard, Philip, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationBlackburn, Anneke, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issueArticle #142
local.bibliographicCitation.startpage1
local.bibliographicCitation.lastpage15
local.identifier.doi10.1186/1476-4598-10-142
dc.date.updated2016-02-24T10:27:45Z
local.identifier.scopusID2-s2.0-81255178599
local.identifier.thomsonID000298246800001
CollectionsANU Research Publications

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