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Cloning and sequence characterization of a non-reducing polyketide synthase gene from the lichen Xanthoparmelia semiviridis

Chooi, Yit-Heng; Stalker, David M; Davis, Meryl A; Fujii, Isao; Elix, John; Louwhoff, Simone; Lawrie, Ann C


Lichens produce a diverse array of secondary metabolites that have shown various biological activities. Of particular interest are the coupled phenolics that originate from polyketide pathways, such as depsides, depsidones and usnic acids, which are produced almost solely by lichens. Based on the presumed catalytic domains required for the synthesis of the key intermediates β-orsellinic acid and methylphloroacetophenone, two pairs of degenerate primers were designed to target specifically the...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Mycological Research
DOI: 10.1016/j.mycres.2007.08.022


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