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Memory T cell RNA rearrangement programmed by heterogeneous nuclear ribonucleoprotein hnRNPLL

Wu, Zuopeng; Jia, Xinying; de la Cruz, Laura; Su, Xun-Cheng; Marzolf, Bruz; Troisch, Pamela; Zak, Daniel; Hamilton, Adam; Whittle, Belinda; Yu, Di; Sheahan, Daniel; Bertram, Edward; Aderem, Alan; Goodnow, Christopher; Hoyne, Gerard; Otting, Gottfried

Description

Differentiation of memory cells involves DNA-sequence changes in B lymphocytes but is less clearly defined in T cells. RNA rearrangement is identified here as a key event in memory T cell differentiation by analysis of a mouse mutation that altered the

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/54021
Source: Immunity
DOI: 10.1016/j.immuni.2008.11.004

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