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Dopaminergic agents affect the ability of brief periods of normal vision to prevent form-deprivation myopia

McCarthy, Siobhan; Megaw, Pam; Devadas , Malini; Morgan, Ian

Description

Placing a translucent diffuser over the eye of a chick causes the eye to grow excessively, resulting in form-deprivation myopia. For chickens kept on a 12:12 h light/dark cycle, removing the diffuser for 3 h during the light period protects against the excessive growth, but if the bird is kept in the dark for this 3-h period, the protective effect is abolished. Injecting dopamine agonists into the eye during this 3-h dark period restores the protective effect, which can be blocked by dopamine...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/53956
Source: Experimental Eye Research
DOI: 10.1016/j.exer.2006.09.018

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