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Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex

Fiedler, Marc; Sanchez-Barrena, Maria Jose; Nekrasov, Maxim; Mieszczanek, Juliusz; Rybin, Vladimir; Muller, Jurg; Evans, Phil; Bienz, Mariann


Pygo and BCL9/Legless transduce the Wnt signal by promoting the transcriptional activity of β-catenin/Armadillo in normal and malignant cells. We show that human and Drosophila Pygo PHD fingers associate with their cognate HD1 domains from BCL9/Legless t

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Molecular Cell
DOI: 10.1016/j.molcel.2008.03.011


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