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An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse

Blewitt, Marnie E; Vickaryous, Nicola K; Hemley, Sarah J; Ashe, Alyson; Bruxner, Timothy J; Preis, Jost I; Arkell, Ruth; Whitelaw, Emma

Description

We have developed a sensitized screen to identify genes involved in gene silencing, using random N-ethyl-N-nitrosourea mutagenesis on mice carrying a variegating GFP transgene. The dominant screen has produced six mutant lines, including both suppressors

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
URI: http://hdl.handle.net/1885/52867
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.0409375102

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