An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse
We have developed a sensitized screen to identify genes involved in gene silencing, using random N-ethyl-N-nitrosourea mutagenesis on mice carrying a variegating GFP transgene. The dominant screen has produced six mutant lines, including both suppressors
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|Source:||PNAS - Proceedings of the National Academy of Sciences of the United States of America|
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