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The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro

Westman, Belinda J; Beeren, Lisa; Grudzien, Ewa; Stepinski, Janusz; Worch, Remigiusz; Zuberek, Joanna; Jemielity, Jacek; Stolarski, Ryszard; Darzynkiewicz, Edward; Rhoads, Robert E; Preiss, Thomas


The eukaryotic initiation factor eIF4E binds the mRNA 5′ cap structure and has a central role during translational initiation. eIF4E and the mechanisms to control its activity have oncogenic properties and thus have become targets for anticancer drug de

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: RNA
DOI: 10.1261/rna.2132505


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