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The NF-κB transcription factor c-Rel is required for Th17 effector cell development in experimental autoimmune encephalomyelitis

Chen, Guobing; Hardy, Kristine; Pagler, Eloisa; Ma, Lina; Lee, Seung Soo; Gerondakis, Steve; Daley, Stephen; Shannon, M Frances

Description

Experimental autoimmune encephalomyelitis (EAE) is a T cell-mediated autoimmune disease involving effector Th subsets such as Th1 and Th17. In this study, we demonstrate that mice lacking the NF-κB transcription factor family member c-Rel (rel -/-), whic

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/52574
Source: Journal of Immunology
DOI: 10.4049/jimmunol.1101757

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