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A chemoenzymatic synthesis of the anti-influenza agent Tamiflu

Matveenko, Maria; Willis, Anthony; Banwell, Martin

Description

The anti-influenza drug Tamiflu® is synthesized from enzymatically derived, enantiomerically pure, and readily available cis-1,2-dihydrocatechol.

dc.contributor.authorMatveenko, Maria
dc.contributor.authorWillis, Anthony
dc.contributor.authorBanwell, Martin
dc.date.accessioned2015-12-10T22:22:09Z
dc.identifier.issn0040-4039
dc.identifier.urihttp://hdl.handle.net/1885/52540
dc.description.abstractThe anti-influenza drug Tamiflu® is synthesized from enzymatically derived, enantiomerically pure, and readily available cis-1,2-dihydrocatechol.
dc.publisherElsevier
dc.sourceTetrahedron Letters
dc.subjectKeywords: bromobenzene; catechol derivative; cis 1,2 dihydrocatechol; oseltamivir; unclassified drug; article; crystal structure; drug structure; drug synthesis; enantioselectivity Acylaziridine; Anti-influenza; cis-1,2-Dihydrocatechol; Synthesis; Tamiflu®
dc.titleA chemoenzymatic synthesis of the anti-influenza agent Tamiflu
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume49
dc.date.issued2008
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationu4005981xPUB249
local.type.statusPublished Version
local.contributor.affiliationMatveenko, Maria, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationWillis, Anthony, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationBanwell, Martin, College of Physical and Mathematical Sciences, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue49
local.bibliographicCitation.startpage7018
local.bibliographicCitation.lastpage7020
local.identifier.doi10.1016/j.tetlet.2008.09.130
dc.date.updated2015-12-09T09:00:57Z
local.identifier.scopusID2-s2.0-54049095827
local.identifier.thomsonID000260843700021
CollectionsANU Research Publications

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