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Unraveling the relationship between structure and stabilization of triarylpyridines as G-quadruplex binding ligands

Smith, N M; Labrunie, Gaelle; Corry, Ben; Tran, Phong Lan Thao; Norret, Marck; Djavaheri-Mergny, Mojgan; Raston, Colin Llewellyn; Mergny, Jean-Louis

Description

A series of novel 2,4,6-triarylpyridines have been synthesized and their interactions with intramolecular G-quadruplexes have been measured by Förster Resonance Energy Transfer (FRET) melting and Fluorescent Intercalator Displacement (FID) assays. A few

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/52522
Source: Organic and Biomolecular Chemistry
DOI: 10.1039/c1ob05560g

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