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A formal total synthesis of platencin

Jackson, Kerrie; Banwell, Martin; Willis, Anthony

Description

(Chemical Equation Presented) The readily available and enantiomerically pure trienes 12 undergo a thermally induced intramolecular Diels-Alder reaction to give the corresponding mixture of compounds 13 and 14. This mixture has been elaborated to an advanced intermediate associated with Nicolaou's recently reported total synthesis of the natural enantiomeric form of the antibiotic platencin (2).

dc.contributor.authorJackson, Kerrie
dc.contributor.authorBanwell, Martin
dc.contributor.authorWillis, Anthony
dc.date.accessioned2015-12-10T22:21:59Z
dc.identifier.issn1523-7060
dc.identifier.urihttp://hdl.handle.net/1885/52453
dc.description.abstract(Chemical Equation Presented) The readily available and enantiomerically pure trienes 12 undergo a thermally induced intramolecular Diels-Alder reaction to give the corresponding mixture of compounds 13 and 14. This mixture has been elaborated to an advanced intermediate associated with Nicolaou's recently reported total synthesis of the natural enantiomeric form of the antibiotic platencin (2).
dc.publisherAmerican Chemical Society
dc.sourceOrganic Letters
dc.subjectKeywords: aminophenol derivative; platencin; polycyclic hydrocarbon; unclassified drug; article; chemical structure; chemistry; synthesis; Aminophenols; Molecular Structure; Polycyclic Compounds
dc.titleA formal total synthesis of platencin
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume10
dc.date.issued2008
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationu4005981xPUB247
local.type.statusPublished Version
local.contributor.affiliationJackson, Kerrie, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationBanwell, Martin, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationWillis, Anthony, College of Physical and Mathematical Sciences, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue20
local.bibliographicCitation.startpage4465
local.bibliographicCitation.lastpage4468
local.identifier.doi10.1021/ol801647h
dc.date.updated2016-02-24T10:22:48Z
local.identifier.scopusID2-s2.0-58149171679
local.identifier.thomsonID000259940600019
CollectionsANU Research Publications

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