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Prospects for lanthanides in structural biology by NMR

Otting, Gottfried


The advent of different lanthanide-binding reagents has made site-specific labelling of proteins with paramagnetic lanthanides a viable proposition. This brings many powerful techniques originally established and demonstrated for paramagnetic metalloproteins into the mainstream of structural biology. The promise is that, by exploiting the long-range effects of paramagnetism, lanthanide labelling will allow the study of larger proteins and protein-ligand complexes with greater ease and accuracy...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Journal of Biomolecular NMR
DOI: 10.1007/s10858-008-9256-0


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