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New Insights into Intracellular Locations and Functions of Heme Oxygenase-1

Dunn, Louise L; Midwinter, Robyn G; Ni, Jun; Hamid, Hafizah A; Stocker, Roland; Parish, Christopher

Description

Significance: Heme oxygenase-1 (HMOX1) plays a critical role in the protection of cells, and the inducible enzyme is implicated in a spectrum of human diseases. The increasing prevalence of cardiovascular and metabolic morbidities, for which current treatment approaches are not optimal, emphasizes the necessity to better understand key players such as HMOX1 that may be therapeutic targets. Recent Advances: HMOX1 is a dynamic protein that can undergo post-translational and structural...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/52216
Source: Antioxidants and Redox Signaling
DOI: 10.1089/ars.2013.5675

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