Skip navigation
Skip navigation

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

Swarbrick, Alexander; Woods, Susan L; Shaw, Alexander; Balakrishnan, Asha; Phua, Yuwei; Nguyen, Akira; Chanthery, Yvan; Lim, Lionel; Ashton, Lesley J; Judson, Robert L; Huskey, Noelle; Blelloch, Robert; Haber, Michelle; Norris, Murray D; Lengyel, Peter; Hackett, Christopher S; Preiss, Thomas; Chetcuti, Albert; Marcusson, Eric G; Weiss, William; L'Etoile, Noelle; Goga, Andrei


A drawback of electrical stimulation for muscle control is that large, fatigable motor units are preferentially recruited before smaller motor units by the lowest-intensity electrical cuff stimulation. This phenomenon limits therapeutic applications because it is precisely the opposite of the normal physiological (orderly) recruitment pattern; therefore, a mechanism to achieve orderly recruitment has been a long-sought goal in physiology, medicine and engineering. Here we demonstrate a...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Nature Medicine
DOI: 10.1038/nm.2227


File Description SizeFormat Image
01_Swarbrick_miR-380-5p_represses_p53_to_2010.pdf1.23 MBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator