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Medical management of paraquat ingestion

Gawarammana, Indika; Buckley, Nicholas


Poisoning by paraquat herbicide is a major medical problem in parts of Asia while sporadic cases occur elsewhere. The very high case fatality of paraquat is due to inherent toxicity and lack of effective treatments. We conducted a systematic search for human studies that report toxicokinetics, mechanisms, clinical features, prognosis and treatment. Paraquat is rapidly but incompletely absorbed and then largely eliminated unchanged in urine within 12-24h. Clinical features are largely due to...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: British Journal of Clinical Pharmacology
DOI: 10.1111/j.1365-2125.2011.04026.x


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