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The synthesis of compounds related to the indole-indoline core of the Vinca alkaloids (+)-vinblastine and (+)-vincristine

Harvey, Michael; Banwell, Martin; Lupton, David

Description

A series of α′-aryl-α′-carbomethoxycycloalk-2-en-1-ones, 16, has been prepared using the Pinhey arylation methodology for introducing the aromatic residue. Subjection of these compounds to Johnson iodination and Pd[0]-catalyzed Ullmann cross-couplin

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/51570
Source: Tetrahedron Letters
DOI: 10.1016/j.tetlet.2008.05.082

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