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Risk factors for craving and relapse in heroin users treated with oral or implant Naltrexone

Hulse, Gary; Ngo, Hanh; Tait, Robert


Background: Oral naltrexone effectively antagonizes heroin, but patient noncompliance limits its utility; sustained-release preparations may overcome this. Few data are available on optimal blood naltrexone levels for preventing craving and/or return to heroin use. This study assesses various risk factors, including blood naltrexone level, for heroin craving and relapse to illicit opioids. Methods: Heroin-dependent persons from a randomized controlled trial of oral versus implant naltrexone...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Biological Psychiatry
DOI: 10.1016/j.biopsych.2010.04.003


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