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A chemoenzymatic total synthesis of ent -narciclasine

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Matveenko, Maria; Banwell, Martin; Willis, Anthony

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The synthesis of the title compound [(-)-1] has been achieved, for the first time, by reacting the aryl boronic acid ester 4 with the aminoconduritol derivative 6 under Suzuki-Miyaura cross-coupling conditions then subjecting the product phenanthridinone

dc.contributor.authorMatveenko, Maria
dc.contributor.authorBanwell, Martin
dc.contributor.authorWillis, Anthony
dc.date.accessioned2015-12-10T22:16:48Z
dc.identifier.issn0040-4020
dc.identifier.urihttp://hdl.handle.net/1885/51112
dc.description.abstractThe synthesis of the title compound [(-)-1] has been achieved, for the first time, by reacting the aryl boronic acid ester 4 with the aminoconduritol derivative 6 under Suzuki-Miyaura cross-coupling conditions then subjecting the product phenanthridinone
dc.publisherElsevier
dc.sourceTetrahedron
dc.subjectKeywords: benzene derivative; boronic acid derivative; bromide; isoenzyme; narciclasine; phenanthrene derivative; toluene dioxygenase; unclassified drug; article; biotransformation; cis isomer; crystal structure; deprotection reaction; drug structure; drug synthesi
dc.titleA chemoenzymatic total synthesis of ent -narciclasine
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume64
dc.date.issued2008
local.identifier.absfor030503 - Organic Chemical Synthesis
local.identifier.ariespublicationu4005981xPUB217
local.type.statusPublished Version
local.contributor.affiliationMatveenko, Maria, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationBanwell, Martin, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationWillis, Anthony, College of Physical and Mathematical Sciences, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue21
local.bibliographicCitation.startpage4817
local.bibliographicCitation.lastpage4826
local.identifier.doi10.1016/j.tet.2008.01.113
dc.date.updated2015-12-09T08:27:12Z
local.identifier.scopusID2-s2.0-42249099621
local.identifier.thomsonID000256042900012
CollectionsANU Research Publications

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