Skip navigation
Skip navigation

A surface transporter family conveys the trypanosome differentiation signal

Dean, Samuel; Marchetti, Rosa; Kirk, Kiaran; Matthews, Keith R.


Microbial pathogens use environmental cues to trigger the developmental events needed to infect mammalian hosts or transmit to disease vectors. The parasites causing African sleeping sickness respond to citrate or cis-aconitate (CCA) to initiate life-cycle development when transmitted to their tsetse fly vector. This requires hypersensitization of the parasites to CCA by exposure to low temperature, conditions encountered after tsetse fly feeding at dusk or dawn. Here we identify a...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Nature
DOI: 10.1038/nature07997


File Description SizeFormat Image
01_Dean_A_surface_transporter_family_2009.pdf645.39 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator