Skip navigation
Skip navigation

Increasing the antitumor efficacy of doxorubicin-loaded liposomes with peptides anchored via a chelator lipid

Herringson, Thomas; Altin, Joseph


The therapeutic efficacy of anticancer drugs like doxorubicin can be significantly increased by their incorporation into liposomes, but an ability to actively target the drug-containing liposomes to tumors could well provide an even greater curative effect. In this work, a commercial preparation of doxorubicin-loaded liposomes (Caelyx) was modified by incorporation of the metal chelator lipid 3(nitrilotriacetic acid)-ditetradecylamine (NTA3-DTDA) to enable engraftment of histidine-tagged...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Journal of Drug Targeting
DOI: 10.3109/1061186X.2010.536984


File Description SizeFormat Image
01_Herringson_Increasing_the_antitumor_2011.pdf840.46 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  12 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator