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Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration

Rutar, Matthew; Natoli, Riccardo; Kozulin, Peter; Valter (Valter-Kocsi), Krisztina; Gatenby, Paul; Provis, Jan


Purpose. To investigate the expression and localization of complement system mRNA and protein in a light-induced model of progressive retinal degeneration. Methods. Sprague-Dawley (SD) rats were exposed to 1000 lux of bright continuous light (BCL) for up

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Investigative Ophthalmology and Visual Science
DOI: 10.1167/iovs.10-7119


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