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Inflammatory S100A9 and S100A12 proteins in Alzheimer's disease

Shepherd, C E; Goyette, Jesse; Utter, V; Rahimi, Ahmed (Farid); Yang, Zheng; Geczy, Carolyn; Halliday, G M


Inflammation, insoluble protein deposition and neuronal cell loss are important features of the Alzheimer's disease (AD) brain. S100B is associated with the neuropathological hallmarks of AD where it is thought to play a role in neuritic pathology. S100A8, S100A9 and S100A12 comprise a new group of inflammation-associated proteins that are constitutively expressed by neutrophils and inducible in numerous inflammatory cells. We investigated expression of S100B, S100A8, S100A9 and S100A12 in...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2005.09.033


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