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Reversible posterior encephalopathy syndrome associated with bortezomib

Terwiel, E; Hanrahan, R; Lueck, Christian; D'Rozario, James

Description

Reversible posterior encephalopathy (RPES) is an uncommon neurological syndrome that is being increasingly reported in association with anti-neoplastic therapies. The first case of reversible posterior encephalopathy associated with the proteosome inhibitor bortezomib is described and the reported experience of the occurrence of RPES with other antineoplastic therapies reviewed. Dysregulation of cerebral vasomotor autoregulation is postulated as the underlying pathophysiology in this case of...[Show more]

dc.contributor.authorTerwiel, E
dc.contributor.authorHanrahan, R
dc.contributor.authorLueck, Christian
dc.contributor.authorD'Rozario, James
dc.date.accessioned2015-12-10T22:14:58Z
dc.identifier.issn1444-0903
dc.identifier.urihttp://hdl.handle.net/1885/50408
dc.description.abstractReversible posterior encephalopathy (RPES) is an uncommon neurological syndrome that is being increasingly reported in association with anti-neoplastic therapies. The first case of reversible posterior encephalopathy associated with the proteosome inhibitor bortezomib is described and the reported experience of the occurrence of RPES with other antineoplastic therapies reviewed. Dysregulation of cerebral vasomotor autoregulation is postulated as the underlying pathophysiology in this case of bortezomib associated RPES.
dc.publisherBlackwell Science Asia
dc.sourceInternal Medicine Journal
dc.subjectKeywords: amlodipine; bortezomib; creatinine; dexamethasone; labetalol; phenytoin; adult; brain edema; case report; creatinine blood level; disease association; disease course; disease severity; drug withdrawal; female; human; kidney disease; mortality; multiple cy Bortezomib; Proteosome inhibitor; Reversible posterior encephalopathy
dc.titleReversible posterior encephalopathy syndrome associated with bortezomib
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume40
dc.date.issued2010
local.identifier.absfor110399 - Clinical Sciences not elsewhere classified
local.identifier.ariespublicationu4201517xPUB203
local.type.statusPublished Version
local.contributor.affiliationTerwiel, E, The Canberra Hospital
local.contributor.affiliationHanrahan, R, The Canberra Hospital
local.contributor.affiliationLueck, Christian, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationD'Rozario, James, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue1
local.bibliographicCitation.startpage69
local.bibliographicCitation.lastpage71
local.identifier.doi10.1111/j.1445-5994.2009.02097.x
dc.date.updated2016-02-24T10:41:31Z
local.identifier.scopusID2-s2.0-76749112047
local.identifier.thomsonID000274410900011
CollectionsANU Research Publications

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