Larena, Maximilian; Regner, Matthias; Lee, Eva; Lobigs, Mario
The immunological correlates for recovery from primary Japanese encephalitis virus (JEV) infection in humans and experimental animals remain poorly defined. To investigate the relative importance of the adaptive immune responses, we have established a mouse model for Japanese encephalitis in which a low-dose virus inoculum was administered into the footpads of adult C57BL/6 mice. In this model, ~60% of the mice developed a fatal encephalitis and a virus burden in the central nervous system...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.