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Does possession of apolipoprotein E ε4 benefit cognitive function in healthy young adults?

Bunce, David; Anstey, Kaarin; Burns, Richard; Christensen, Helen; Easteal, Simon

Description

There is considerable evidence that the apolipoprotein E (APOE) e{open}4 allele is associated with cognitive deficits in older persons, and is a risk factor for dementia. However, it has recently been suggested that possession of the e{open}4 allele may benefit cognition in early adulthood. We tested this possibility in 5445 community-dwelling persons aged 20-24, 40-44, and 60-64 years using a comprehensive battery of cognitive measures. As the APOE e{open}2 allele may offer protection against...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/50240
Source: Neuropsychologia
DOI: 10.1016/j.neuropsychologia.2011.02.042

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