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Creating Functional Artificial Proteins

Razeghifard, Mohammad; Wallace, Brett; Pace, Ronald; Wydrzynski, Thomas

Description

Much is now known about how protein folding occurs, through the sequence analysis of proteins of known folding geometry and the sequence/ structural analysis of proteins and their mutants. This has allowed not only the modification of natural proteins but also the construction of de novo polypeptides with predictable folding patterns. Structure/ function analysis of natural proteins is used to construct derived versions that retain a degree of biological activity. The constructed versions made...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/50218
Source: Current Protein and Peptide Science
DOI: 10.2174/138920307779941479

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