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Formal total synthesis of triptolide

Miller, Natalie; Willis, Anthony; Sherburn, Michael


A new approach to the medicinally-important natural product triptolide is significantly shorter than previous syntheses, highly convergent and avoids the use of protecting groups; key features include two Diels-Alder reactions and a new deoxygenative aromatisation process.

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Chemical Communications
DOI: 10.1039/b718754h


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