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Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression

Hui, Jason M; Sud, Archana; Farrell, Geoffrey; Bandara, Priyanka; Byth, Karen; Kench, James; McCaughan, Geoffrey W; George, Jacob


Background & Aims: Chronic hepatitis C virus infection is associated with an increased prevalence of type 2 diabetes. We hypothesized that virus-induced insulin resistance may be a mechanism for fibrogenesis in chronic hepatitis C virus infection. Methods: In 260 hepatitis C virus-infected subjects, we examined the relationship between histological findings and anthropometric and biochemical data, including insulin resistance determined by the homeostasis model assessment (HOMA-IR). We also...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Gastroenterology
DOI: 10.1053/j.gastro.2003.08.032


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