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A fresh look at NASH pathogenesis. Part 1: The metabolic movers

Larter, Claire; Chitturi, Shivakumar; Heydet, Deborah; Farrell, Geoffrey


The strong relationship between over-nutrition, central obesity, insulin resistance/metabolic syndrome and non-alcoholic fatty liver disease (NAFLD) suggest pathogenic interactions, but key questions remain. NAFLD starts with over-nutrition, imbalance between energy input and output for which the roles of genetic predisposition and environmental factors (diet, physical activity) are being redefined. Regulation of energy balance operates at both central nervous system and peripheral sites,...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Journal of Gastroenterology and Hepatology
DOI: 10.1111/j.1440-1746.2010.06253.x


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