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Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo

Sun, Ramon; Fadia, Mitali; Dahlstrom, Jane; Parish, Christopher; Board, Philip; Blackburn, Anneke

Description

The glycolytic phenotype is a widespread phenomenon in solid cancer forms, including breast cancer. Dichloroacetate (DCA) has recently been proposed as a novel and relatively non-toxic anti-cancer agent that can reverse the glycolytic phenotype in cancer

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/49627
Source: Breast Cancer Research and Treatment
DOI: 10.1007/s10549-009-0435-9

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