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Unique IL-13Ralpha2-based HIV-1 vaccine strategy to enhance mucosal immunity, CD8 þ T-cell avidity and protective immunity

Trivedi, Shubhanshi; Stambas, John; Jackson, Ronald; Ranasinghe, Charani

Description

We have established that mucosal immunization can generate high-avidity human immunodeficiency virus (HIV)-specific CD8 + T cells compared with systemic immunization, and interleukin (IL)-13 is detrimental to the functional avidity of these T cells. We ha

dc.contributor.authorTrivedi, Shubhanshi
dc.contributor.authorStambas, John
dc.contributor.authorJackson, Ronald
dc.contributor.authorRanasinghe, Charani
dc.date.accessioned2015-12-10T22:12:18Z
dc.identifier.issn1933-0219
dc.identifier.urihttp://hdl.handle.net/1885/49578
dc.description.abstractWe have established that mucosal immunization can generate high-avidity human immunodeficiency virus (HIV)-specific CD8 + T cells compared with systemic immunization, and interleukin (IL)-13 is detrimental to the functional avidity of these T cells. We ha
dc.publisherNature Publishing Group
dc.sourceMucosal Immunology
dc.subjectKeywords: CD8 antigen; chemokine; cytokine; Human immunodeficiency virus vaccine; interleukin 13 receptor alpha2; recombinant vaccine; animal cell; animal experiment; animal tissue; antigen presenting cell; article; CD8+ T lymphocyte; cellular immunity; drug bindin
dc.titleUnique IL-13Ralpha2-based HIV-1 vaccine strategy to enhance mucosal immunity, CD8 þ T-cell avidity and protective immunity
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume6
dc.date.issued2013
local.identifier.absfor110799 - Immunology not elsewhere classified
local.identifier.ariespublicationu6800332xPUB188
local.type.statusPublished Version
local.contributor.affiliationRanasinghe, Charani, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationTrivedi, Shubhanshi, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationStambas, John, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationJackson, Ronald, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue6
local.bibliographicCitation.startpage1068
local.bibliographicCitation.lastpage1080
local.identifier.doi10.1038/mi.2013.1
dc.date.updated2016-02-24T11:38:06Z
local.identifier.scopusID2-s2.0-84883598341
local.identifier.thomsonID000325916800002
CollectionsANU Research Publications

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